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Article

Interactions of release factor RF3 with the translation machinery.

Molecular genetics and genomics : MGG - 1 Aug 2015

O'Connor Michael

Abstract excerpt

The bacterial release factor RF3 is a GTPase that has been implicated in multiple, incompletely understood steps of protein synthesis. This study explores the genetic interaction of RF3 with other components of the translation machinery. RF3 contributes to translation termination by recycling the class I release factors RF1 and RF2 off post-termination ribosomes. RF3 has also been implicated in dissociation of...

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Share to Escherichia coli Proteins
Share to Microbial Viability
Share to Peptide Chain Termination, Translational

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Peptide Termination Factors

Share to Protein Biosynthesis

Share to Ribosomes

Share to RNA, Transfer, Amino Acyl

Share to Salmonella enterica

Source

Identifiers

PMID: 25636454
DOI: 10.1007/s00438-015-0994-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Interactions of release factor RF3 with the translation machinery.PMID 25636454Read ↗

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Release factor RF3 abolishes competition between release factor RF1 and ribosome recycling factor (RRF) for a ribosome binding site.Semantic proximity Read ↗

Alterations in the ribosomal protein bL12 of E. coli affecting the initiation, elongation and termination of protein synthesis.Semantic proximity Read ↗

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