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Article

Influence of Flexible "ω" on the Activity of E. coli RNA Polymerase: A Thermodynamic Analysis.

Biophysical journal - 14 Mar 2017

Bhowmik Debipreeta, Bhardwaj Neerupma, Chatterji Dipankar

Abstract excerpt

The Escherichia coli RNA polymerase (RNAP) is a multisubunit protein complex containing the smallest subunit, ω. Despite the evolutionary conservation of ω and its role in assembly of RNAP, E. coli mutants lacking rpoZ (codes for ω) are viable due to the association of RNAP with the global chaperone protein GroEL. With an aim to get better insight into the structure and functional role of ω, we isolated a...

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Identifiers

PMID: 28297649
DOI: 10.1016/j.bpj.2017.01.015
PMCID: PMC5355486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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