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Article

Association of IL-17F rs2397084 (E126G), rs11465553 (V155I) and rs763780 (H161R) variants with rheumatoid arthritis and their effects on the stability of protein.

PloS one - 1 Jan 2023

Ali Yasir, Kausar Masood, Farooq Mazhar, Farooqi Nadia, Ul Islam Zia, Khan Suleman, Aman Aisha, Khan Naveed, Kamil Atif, Jalil Fazal

Abstract excerpt

Interleukin-17F (IL-17F), considered a pro-inflammatory cytokine, has been shown to contribute to skeletal tissue degradation and hence chronic inflammation in rheumatoid arthritis (RA). In this study we utilized bioinformatics tools to analyze the effect of three exonic SNPs (rs2397084, rs11465553, and rs763780) on the structure and function of the IL-17F gene, and evaluated their association with RA in...

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Share to Arthritis, Rheumatoid
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Source

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Identifiers

PMID: 37751416
DOI: 10.1371/journal.pone.0285874
PMCID: PMC10522029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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