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Three polymorphisms in interleukin-1β gene and risk for breast cancer: a meta-analysis.

Breast cancer research and treatment - 1 Dec 2010

Liu Xiaoan, Wang Zhanwei, Yu Jinhua, Lei Gang, Wang Shui

Abstract excerpt

Interleukin-1β (IL-1β), which is involved in inflammatory and immunological responses, plays an important role in the development and progression of breast cancer. Three functional single nucleotide polymorphisms (SNPs) identified in IL-1β gene are thought to influence breast cancer risk. The results of the association between IL-1β polymorphisms and breast cancer remain inconsistent. Therefore, we conducted a...

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PMID: 20437198
DOI: 10.1007/s10549-010-0910-3

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