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The Importance of REST for Development and Function of Beta Cells

23 Feb 2017

Abstract excerpt

Beta cells are defined by the genes they express, many of which are specific to this cell type, and ensure a specific set of functions. Beta cells are also defined by a set of genes they should not express (in order to function properly), and these genes have been called forbidden genes. Among these, the transcriptional repressor RE-1 Silencing Transcription factor (REST) is expressed in most cells of the body,...

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Identifiers

PMID: 28286748
DOI: 10.3389/fcell.2017.00012

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The Importance of REST for Development and Function of Beta CellsPMID 28286748Read ↗

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C-terminal domain small phosphatase 1 and MAP kinase reciprocally control REST stability and neuronal differentiation.Semantic proximity Read ↗

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Genome-wide assessment of REST binding profiles reveals distinctions between human and mouse hippocampusSemantic proximity Read ↗

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