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Article

Enhanced susceptibility of triple transgenic Alzheimer's disease (3xTg-AD) mice to acute infection.

Journal of neuroinflammation - 11 Mar 2017

Montacute Rebecca, Foley Kerry, Forman Ruth, Else Kathryn Jane, Cruickshank Sheena Margaret, Allan Stuart McRae

Abstract excerpt

BACKGROUND: Infection is a recognised risk factor for Alzheimer's disease (AD) and can worsen symptoms in established disease. AD patients have higher rates of infection and are more likely to require hospital admissions due to infections than individuals without dementia. Infections have also been found to increase the risk of those over 84 years of age being diagnosed with dementia. However, few studies have...

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Identifiers

PMID: 28284226
DOI: 10.1186/s12974-017-0826-5
PMCID: PMC5346250

Genes

TNF
CCL5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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