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Article

MicroRNA-Related Polymorphisms in PI3K/Akt/mTOR Pathway Genes Are Predictive of Limited-Disease Small Cell Lung Cancer Treatment Outcomes.

BioMed research international - 1 Jan 2017

Jiang Wei, Zhang Wenjue, Wu Lihong, Liu Lipin, Men Yu, Wang Jingbo, Liang Jun, Hui Zhouguang, Zhou Zongmei, Bi Nan, Wang Luhua

Abstract excerpt

The phosphoinositide-3 kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling pathway plays an important role in cancer progression and treatment, including that of small cell lung cancer (SCLC), a disease with traditionally poor prognosis. Given the regulatory role of microRNA (miRNA) in gene expression, we examined the association of single nucleotide polymorphisms (SNPs) at miRNA-binding sites of...

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Source

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Identifiers

PMID: 28280736
DOI: 10.1155/2017/6501385
PMCID: PMC5322445

Genes

MTOR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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