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Development and validation of a blood-based genomic mutation signature for predicting the risk of brain metastases in non-small cell lung cancer

2024-02-09

Abstract excerpt

<title>Abstract</title> <p>Purpose Available research indicates that the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway is significantly correlated with lung cancer brain metastasis (BM). This study established a clinical predictive model for assessing the risk of BM based on the mTORC1-related single nucleotide polymorphisms (SNPs). Methods The clinical data of 395 patients with non-small c...

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Literature Corpus work
74107760-5c75-5c0e-96ff-6198f6c6c2d3
DOI
10.21203/rs.3.rs-3927682/v1
Open publication

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Development and validation of a blood-based genomic mutation signature for predicting the risk of brain metastases in non-small cell lung cancerDOI 10.21203/rs.3.rs-3927682/v1
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