Article
Association between polymorphisms of autophagy pathway and responses in non-small cell lung cancer patients treated with platinum-based chemotherapy.
Yi chuan = Hereditas - 20 Mar 2017
Wang Shi-ming, Song Xiao, Zhao Xue-ying, Chen Hong-yan, Wang Jiu-cun, Wu Jun-jie, Gao Zhi-qiang, Qian Ji, Bai Chun-xue, Li Qiang, Han Bao-hui, Lu Da-ru
Abstract excerpt
Platinum-based chemotherapy is an important treatment for non-small cell lung cancer. However, the effectiveness of the treatment varies among the patients. We investigated the association between DNA polymorphisms of the autophagy pathway and responses of such treatment among 1004 Chinese patients. Ninety-nine SNPs located on 13 genes of the autophagy pathway were genotyped and assessed for their association...
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