Article
Development and validation of a nomogram model based on blood-based genomic mutation signature for predicting the risk of brain metastases in non-small cell lung cancer.
BMC pulmonary medicine - 27 Dec 2024
Fang Jiabin, Chen Lina, Pan Shuyao, Li Qing, Liu Siqiang, Chen Sufang, Yang Xiaojie, Zhang Qiongyao, Chen Yusheng, Li Hongru
Abstract excerpt
PURPOSE: Available research indicates that the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway is significantly correlated with lung cancer brain metastasis (BM). This study established a clinical predictive model for assessing the risk of BM based on the mTORC1-related single nucleotide polymorphisms (SNPs). METHODS: In this single-center retrospective study, 395 patients with non-small cell...
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