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Article

Blockade of CCR5 receptor prevents M2 microglia phenotype in a microglia-glioma paradigm.

Neurochemistry international - 1 Sept 2017

Laudati Emilia, Currò Diego, Navarra Pierluigi, Lisi Lucia

Abstract excerpt

Microglia express chemokines and their cognate receptors that were found to play important roles in many processes required for tumor development, such as tumor growth, proliferation, invasion, and angiogenesis. Among the chemokine receptor, CCR5 have been documented in different cancer models; in particular, CCR5 is highly expressed in human glioblastoma, where it is associated to poor prognosis. In the present...

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Share to CCR5 Receptor Antagonists
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28279751
DOI: 10.1016/j.neuint.2017.03.002

Genes

CCR5
ARG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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