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Article

The ISWI ATPase Smarca5 (Snf2h) Is Required for Proliferation and Differentiation of Hematopoietic Stem and Progenitor Cells.

Stem cells (Dayton, Ohio) - 1 Jun 2017

Kokavec Juraj, Zikmund Tomas, Savvulidi Filipp, Kulvait Vojtech, Edelmann Winfried, Skoultchi Arthur I, Stopka Tomas

Abstract excerpt

The imitation switch nuclear ATPase Smarca5 (Snf2h) is one of the most conserved chromatin remodeling factors. It exists in a variety of oligosubunit complexes that move DNA with respect to the histone octamer to generate regularly spaced nucleosomal arrays. Smarca5 interacts with different accessory proteins and represents a molecular motor for DNA replication, repair, and transcription. We deleted Smarca5 at...

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Identifiers

PMID: 28276606
DOI: 10.1002/stem.2604
PMCID: PMC5927548

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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