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Article

TAF250 is required for multiple developmental events in Drosophila.

Proceedings of the National Academy of Sciences of the United States of America - 1 Feb 2000

Wassarman D A, Aoyagi N, Pile L A, Schlag E M

Abstract excerpt

The TFIID transcription initiation complex is composed of TBP and multiple TAFs. Studies in unicellular systems indicate that TAF250 is required for progression through G(1)/S of the cell cycle and repression of apoptosis. Here we extend these in vivo studies by determining the developmental requirements for TAF250 in a multicellular organism, Drosophila. TAF250 mutants were isolated in a genetic screen that also...

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Identifiers

PMID: 10655500
DOI: 10.1073/pnas.97.3.1154
PMCID: PMC15553

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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