Article
Pan-Cancer Analysis of Genomic Sequencing Among the Elderly.
International journal of radiation oncology, biology, physics - 15 Jul 2017
Wahl Daniel R, Nguyen Paul L, Santiago Maria, Yousefi Kasra, Davicioni Elai, Shumway Dean A, Speers Corey, Mehra Rohit, Feng Felix Y, Osborne Joseph R, Spratt Daniel E
Abstract excerpt
PURPOSE: We hypothesized that elderly patients might have age-specific genetic abnormalities yet be underrepresented in currently available sequencing repositories, which could limit the effect of sequencing efforts for this population. METHODS AND MATERIALS: Leveraging The Cancer Genome Atlas (TCGA) data portal, 9 tumor types were analyzed. The frequency distribution of cancer by age was determined and compared...
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