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Article

Foxc1 and Foxc2 in the Neural Crest Are Required for Ocular Anterior Segment Development.

Investigative ophthalmology & visual science - 1 Mar 2017

Seo Seungwoon, Chen Lisheng, Liu Wenzhong, Zhao Demin, Schultz Kathryn M, Sasman Amy, Liu Ting, Zhang Hao F, Gage Philip J, Kume Tsutomu

Abstract excerpt

Purpose: The large Forkhead (Fox) transcription factor family has essential roles in development, and mutations cause a wide range of ocular and nonocular disease. One member, Foxc2 is expressed in neural crest (NC)-derived periocular mesenchymal cells of the developing murine eye; however, its precise role in the development, establishment, and maintenance of the ocular surface has yet to be investigated....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28253399
DOI: 10.1167/iovs.16-21217
PMCID: PMC5361455

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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