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Transcription factor TFAP2B up-regulates human corneal endothelial cell–specific genes during corneal development and maintenance

14 Dec 2018

Abstract excerpt

The corneal endothelium, which originates from the neural crest via the periocular mesenchyme (PM), is crucial for maintaining corneal transparency. The development of corneal endothelial cells (CECs) from the neural crest is accompanied by the expression of several transcription factors, but the contribution of some of these transcriptional regulators to CEC development is incompletely understood. Here, we...

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PMID: 30552118
DOI: 10.1074/jbc.ra118.005527

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