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Article

Relationship between neural crest cell specification and rare ocular diseases.

Journal of neuroscience research - 1 Jan 2019

Akula Monica, Park Jeong Won, West-Mays Judith A

Abstract excerpt

Development of the eye is closely associated with neural crest cell migration and specification. Eye development is extremely complex, as it requires the working of a combination of local factors, receptors, inductors, and signaling interactions between tissues such as the optic cup and periocular mesenchyme (POM). The POM is comprised of neural crest-derived mesenchymal progenitor cells that give rise to...

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Source

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Identifiers

PMID: 29660784
DOI: 10.1002/jnr.24245
PMCID: PMC6191383

Genes

FOXC1
FOXE3
PAX6
PITX2
PITX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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