Article

Primary cilia deficiency in neural crest cells causes Anterior Segment Dysgenesis

2019-08-30

Abstract excerpt

<h4>ABSTRACT</h4> During eye embryogenesis, neural crest cells (NCC) of the periocular mesenchyme (POM) migrate to the anterior segment (AS) of the eye and then differentiate into the corneal stroma and endothelium, ciliary body, iris stroma, and the trabecular meshwork. Defective development of these structures leads to anterior segment dysgenesis (ASD) that in 50% of the cases leads to glaucoma, a leading cause...

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Literature Corpus work: 060ba38e-c8eb-5f7b-b2aa-d40f0bad195f
DOI: 10.1101/752105

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