Article
The Role of Mutation Rates of GNAQ or GNA11 in Cases of Uveal Melanoma in Japan.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Oct 2018
Ominato Jun, Fukuchi Takeo, Sato Ayako, Yamaguchi Naoyuki, Kobayashi Kazue, Cho Hiroyuki, Oyama Tokuhide, Ajioka Yoichi
Abstract excerpt
GNAQ and GNA11 mutations are thought to be important for the tumorigenesis of uveal melanoma. Although previous studies have reported on mutation rates in cases of uveal melanoma, presently, no such report for the Japanese population exists. In this study, we examined the frequency of GNAQ and GNA11 somatic mutations in cases of uveal melanoma in Japan and their relationship with clinicopathologic features or...
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