Article

Uveal Melanoma: Molecular and Genetic Mechanisms of Development and Therapeutic Approaches

2024-04-01

Abstract excerpt

Abstract Uveal melanoma (UM) is a neuroectodermal tumor that results from malignant transformation of melanocytes in the eye uvea, including the iris, the ciliary body, and the choroid. UM accounts for 5% of all melanoma cases and is extremely aggressive with half of the UM patients developing metastases within the first 1‒2 years after tumor development. Molecular mechanisms of UM carcinogenesis are poorly unders...

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Literature Corpus work: 645bf093-e9dd-514b-8f5b-fbe788fcc6c6
DOI: 10.1134/s0026893324020183

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