Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel linkage disequilibrium clustering algorithm identifies new lupus genes on meta-analysis of GWAS datasets.

Immunogenetics - 1 May 2017

Saeed Mohammad

Abstract excerpt

Systemic lupus erythematosus (SLE) is a complex disorder. Genetic association studies of complex disorders suffer from the following three major issues: phenotypic heterogeneity, false positive (type I error), and false negative (type II error) results. Hence, genes with low to moderate effects are missed in standard analyses, especially after statistical corrections. OASIS is a novel linkage disequilibrium...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Cluster Analysis
Share to Datasets as Topic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Markers

Share to Genome-Wide Association Study

Share to Linkage Disequilibrium

Share to Lupus Erythematosus, Systemic

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 28246883
DOI: 10.1007/s00251-017-0976-8
PMCID: PMC5400794

Genes

IFIH1
LATS2
MON2
NCOA3
RBFOX1
SNX6
TNFAIP6
TNIP1
TTF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel linkage disequilibrium clustering algorithm identifies new lupus genes on meta-analysis of GWAS datasets.PMID 28246883Read ↗

High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry.Semantic proximity Read ↗

Investigating Overlapping Genetic Factors and Novel Causal Genes in Autoimmune Diseases: A Transcriptome‐Wide Association and Multiomics StudySemantic proximity Read ↗

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.Semantic proximity Read ↗

Confirmation of five novel susceptibility loci for systemic lupus erythematosus (SLE) and integrated network analysis of 82 SLE susceptibility loci.Semantic proximity Read ↗

Novel Genomic Risk Loci shared between Juvenile Idiopathic Arthritis and other HLA-associated Autoimmune DiseasesSemantic proximity Read ↗

Transmission disequilibrium analysis of whole genome data in childhood-onset systemic lupus erythematosus.Semantic proximity Read ↗

Review of recent genome-wide association scans in lupus.Semantic proximity Read ↗

A targeted association study in systemic lupus erythematosus identifies multiple susceptibility alleles.Semantic proximity Read ↗

Functional relevance for associations between genetic variants and systemic lupus erythematosus.Semantic proximity Read ↗

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.Semantic proximity Read ↗

GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.Semantic proximity Read ↗

Shared Genetic Basis Between Systemic Lupus Erythematosus and Inflammatory Bowel Disease in East Asian Ancestry: A Genome-Wide Cross-trait Analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.