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Article

Shared Genetic Basis Between Systemic Lupus Erythematosus and Inflammatory Bowel Disease in East Asian Ancestry: A Genome-Wide Cross-trait Analysis.

Inflammatory bowel diseases - 1 Feb 2026

Mo Xiaoxiao, Mo Hui, Wang Chao, Pu Qiuyi, Sha Lanlan, Zhao Letian, Zhang Zhengdong, Wang Ting, Wu Dongmei

Abstract excerpt

Systemic lupus erythematosus (SLE) and inflammatory bowel disease (IBD) are both categorized as autoimmune disorders and have similar non-specific gastrointestinal symptoms. SLE and IBD have shown shared genetic architecture in European ancestry; however, given the ancestry-specificity of genetic architecture, the shared genetic structure in East Asian ancestry remains unclear. This study reveals significant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41309137
DOI: 10.1093/ibd/izaf297

Genes

ATG16L2
HIC2
TULP1
UBE2L3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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