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Article

CCR7+ selected gene-modified T cells maintain a central memory phenotype and display enhanced persistence in peripheral blood in vivo.

Journal for immunotherapy of cancer - 1 Jan 2017

Kueberuwa Gray, Gornall Hannah, Alcantar-Orozco Erik Marcelo, Bouvier Deborah, Kapacee Zainul Abedin, Hawkins Robert Edward, Gilham David Edward

Abstract excerpt

BACKGROUND: Adoptive T cell immunotherapy (ATCT) for cancer entails infusing patients with T cells that recognise and destroy tumour cells. Efficient engraftment of T cells and persistence in the circulation correlate with favourable clinical outcomes. T cells of early differentiation possess an increased capacity for proliferation and therefore persistence, using these cells for ATCT could therefore lead to...

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Share to CCR7 gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28239467
DOI: 10.1186/s40425-017-0216-7
PMCID: PMC5319186

Genes

CCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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