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Article

Potent CAR-T cells engineered with Sleeping Beauty transposon vectors display a central memory phenotype.

Gene therapy - 1 Feb 2021

Ivics Zoltán

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Share to DNA Transposable Elements
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32139891
DOI: 10.1038/s41434-020-0138-8

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Potent CAR-T cells engineered with Sleeping Beauty transposon vectors display a central memory phenotype.PMID 32139891Read ↗

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Transposon-mediated generation of CAR-T cells shows efficient anti B-cell leukemia response after ex vivo expansionSemantic proximity Read ↗

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Transposon-Based CAR T Cells in Acute Leukemias: Where Are We Going?Semantic proximity Read ↗

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<i>Sleeping Beauty</i> mutagenesis identifies <i>BACH2</i> and other regulators of CD8 <sup>+</sup> T cell exhaustion, persistence <i>in vivo</i> , and CAR-T function under tumor-associated chronic antigen stimulationSemantic proximity Read ↗

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Redirecting Specificity of T-Cell Populations For CD19 Using the <i>Sleeping Beauty</i> SystemSemantic proximity Read ↗

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Current Non-Viral-Based Strategies to Manufacture CAR-T CellsSemantic proximity Read ↗

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