Article
A haplotype spanning P2X7R, P2X4R and CAMKK2 may mark susceptibility to pulmonary non-tuberculous mycobacterial disease.
Immunogenetics - 1 May 2017
Halstrom Samuel, Cherry Catherine L, Black Michael, Thomson Rachel, Goullee Hayley, Baltic Svetlana, Allcock Richard, Temple Suzanna E L, Price Patricia
Abstract excerpt
Despite widespread exposure to potentially pathogenic mycobacteria present in the soil and in domestic water supplies, it is not clear why only a small proportion of individuals contract pulmonary nontuberculous mycobacterial (NTM) infections. Here, we explore the impact of polymorphisms within three genes: P2X ligand gated ion channel 7 (P2X7R), P2X ligand gated ion channel 4 (P2X4R) and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.