ALKBH7 Variant Related to Prostate Cancer Exhibits Altered Substrate Binding.

doi:10.1371/journal.pcbi.1005345

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Article

ALKBH7 Variant Related to Prostate Cancer Exhibits Altered Substrate Binding.

PLoS computational biology - 1 Feb 2017

Walker Alice R, Silvestrov Pavel, Müller Tina A, Podolsky Robert H, Dyson Gregory, Hausinger Robert P, Cisneros Gerardo Andrés

Abstract excerpt

The search for prostate cancer biomarkers has received increased attention and several DNA repair related enzymes have been linked to this dysfunction. Here we report a targeted search for single nucleotide polymorphisms (SNPs) and functional impact characterization of human ALKBH family dioxygenases related to prostate cancer. Our results uncovered a SNP of ALKBH7, rs7540, which is associated with prostate...

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PMID: 28231280
DOI: 10.1371/journal.pcbi.1005345
PMCID: PMC5322872

Genes

ALKBH7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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