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Article

Three haplotypes associated with CYP2A6 phenotypes in Caucasians.

Pharmacogenetics and genomics - 1 Sept 2005

Haberl Michael, Anwald Birgit, Klein Kathrin, Weil Regina, Fuss Christine, Gepdiremen Akçahan, Zanger Ulrich M, Meyer Urs A, Wojnowski Leszek

Abstract excerpt

The human cytochrome P450 2A6 (CYP2A6) enzyme metabolizes several xenobiotic compounds of clinical or toxicological importance. We aimed to identify genetic variants and major CYP2A6 haplotypes associated with CYP2A6 phenotypic variation. CYP2A6 mRNA level, protein level, activity and haplotypes were determined in Caucasian liver samples via real-time polymerase chain reaction, Western blot, coumarin...

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Source

Identifiers

PMID: 16041240
DOI: 10.1097/01.fpc.0000171517.22258.f1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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