Article
A Variant in the Precursor of MicroRNA-146a is Responsible for Development of Erectile Dysfunction in Patients with Chronic Prostatitis via Targeting NOS1.
Medical science monitor : international medical journal of experimental and clinical research - 20 Feb 2017
Ding Jian, Tang Yuxin, Tang Zhengyan, Zhang Xiangyang, Wang Guilin
Abstract excerpt
BACKGROUND The morbidity of erectile dysfunction (ED) has been found to be substantially increased in patients with chronic prostatitis (CP). Accumulating evidence shows that single-nucleotide polymorphism (SNP) located in pre-miRNA or mature microRNA may affect the processing of microRNA (miRNA) and alter the expression of the miRNA, as well as its target gene. In this study we investigated the association...
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