Article
Rs2910164 in microRNA‑146a confers an elevated risk of depression in patients with coronary artery disease by modulating the expression of NOS1.
Molecular medicine reports - 1 Jul 2018
Zhang Xinling, Huo Qianqian, Sun Wei, Zhang Chunxiang, Wu Zongyin, Xing Bing, Li Qiang
Abstract excerpt
Depression has been well established as an independent predictor of mortality and cardiac morbidity rates in patients with coronary artery disease (CAD). Evidence has shown that single nucleotide polymorphisms located in pre‑microRNA (miRNA) or mature miRNA may modify various biological processes and affect the process of carcinogenesis, and the downregulation of neuronal nitric oxide synthase 1 (NOS1) can induce...
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