Article
A single nucleotide polymorphism in microRNA-146a is associated with the risk for nasopharyngeal carcinoma.
Molecular carcinogenesis - 1 Nov 2013
Lung Raymond Wai-Ming, Wang Xingyan, Tong Joanna Hung-Man, Chau Shuk-Ling, Lau Kin-Mang, Cheng Shuk-Hang, Woo John Kong-Sang, Woo Jean, Leung Ping-Chung, Ng Margaret Heung-Ling, Tang Nelson Leung-Sang, To Ka-Fai
Abstract excerpt
A common GC polymorphism within miRNA-146a precursor region (rs2910164) has been associated with the risk of various cancers despite the underlying mechanism is unclear. In the current study, we aimed to examine the role of rs2910164 in the pathogenesis and predisposition to nasopharyngeal carcinoma (NPC). The GC polymorphism in 233 NPC patients, 173 matched controls and 3613 healthy elderly subjects in our...
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