Polymorphism of the pre-miR-146a is associated with risk of cervical cancer in a Chinese population.

doi:10.1016/j.ygyno.2011.03.032

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Article

Polymorphism of the pre-miR-146a is associated with risk of cervical cancer in a Chinese population.

Gynecologic oncology - 1 Jul 2011

Yue Cong, Wang Meilin, Ding Bo, Wang Wei, Fu Shilong, Zhou Delan, Zhang Zhengdong, Han Suping

Abstract excerpt

OBJECTIVE: MicroRNAs are tiny non-coding RNAs that reportedly play an important role in numerous physiological processes. A G>C polymorphism (rs2910164) is located on the passenger strand of the precursor of miR-146a, which could alter mature miR-146a expression. We hypothesized that a possible association exists between miR-146a gene polymorphisms and cervical cancer risk in a population-based control study of...

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PMID: 21529907
DOI: 10.1016/j.ygyno.2011.03.032

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