Article
rs2910164 Polymorphism Confers a Decreased Risk for Pulmonary Hypertension by Compromising the Processing of microRNA-146a.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2015
Liu Haitao, Chen Mai, Wu Feng, Li Fei, Yin Tao, Cheng Hexiang, Li Weijie, Liu Bing, Wang Qiong, Tao Ling
Abstract excerpt
OBJECTIVE: To identify the association between rs2910164 polymorphism and development of pulmonary hypertension, as well as underlying molecular mechanism. METHODS AND RESULTS: 281 patients diagnosed with pulmonary hypertension and 325 normal controls were recruited, and rs2910164 genotype was determined in each participant: As a result, the rs2910164 polymorphism was significantly associated with the development...
Read the complete abstract on PubMed