Article
No Association of MicroRNA-146a rs2910164 Polymorphism and Risk of Primary Gout Development in Chinese Han Populations: A Case-control Study.
Current rheumatology reviews - 1 Jan 2021
Qing Yu-Feng, Zhang Quan-Bo, Dai Fei, Huang Yu-Qin, Zheng Jian-Xiong, Tang Yi-Ping, Dong Zeng-Rong, Wang Shun-Bing
Abstract excerpt
BACKGROUND: Previous studies demonstrated that MicroRNA-146a (miR-146a) plays an important role in the regulation of autoinflammatory diseases including primary gout. The G/C polymorphism (rs2910164) in the precursor sequence of miR-146a caused its stem region to change from G: U to C: U,which can contribute to the susceptibility of human diseases. However, no genetic relevance studies of miR-146a gene...
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