Article
The Genomic Impact of DNA CpG Methylation on Gene Expression; Relationships in Prostate Cancer.
Biomolecules - 14 Feb 2017
Long Mark D, Smiraglia Dominic J, Campbell Moray J
Abstract excerpt
The process of DNA CpG methylation has been extensively investigated for over 50 years and revealed associations between changing methylation status of CpG islands and gene expression. As a result, DNA CpG methylation is implicated in the control of gene expression in developmental and homeostasis processes, as well as being a cancer-driver mechanism. The development of genome-wide technologies and sophisticated...
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