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Article

Epigenomic profiling of DNA methylation in paired prostate cancer versus adjacent benign tissue

18 Sept 2015

Abstract excerpt

BACKGROUND: Aberrant DNA methylation may promote prostate carcinogenesis. We investigated epigenome-wide DNA methylation profiles in prostate cancer (PCa) compared to adjacent benign tissue to identify differentially methylated CpG sites. METHODS: The study included paired PCa and adjacent benign tissue samples from 20 radical prostatectomy patients. Epigenetic profiling was done using the Infinium...

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PMID: 26383847
DOI: 10.1002/pros.23093

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