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Integrating Multi-Omics Data to Uncover Prostate Tissue DNA Methylation Biomarkers and Target Genes for Prostate Cancer Risk.

Molecular carcinogenesis - 1 Jan 2025

Liu Shuai, Zhu Jingjing, Green Dylan, Zhong Hua, Long Quan, Wu Chong, Wang Liang, Deng Youping, Wu Lang

Abstract excerpt

Previous studies have indicated that specific CpG sites may be linked to the risk of prostate cancer (PCa) by regulating the expression of PCa target genes. However, most existing studies aim to identify DNA methylation (DNAm) biomarkers through blood tissue genetic instruments, which impedes the identification of relevant biomarkers in prostate tissue. To identify PCa risk-associated CpG sites in prostate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39400371
DOI: 10.1002/mc.23828
PMCID: PMC12009774

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