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Article

DNA methylation alterations in prostate cancer: from diagnosis to treatment

1 Feb 2025

Abstract excerpt

Abstract: Epigenetics, particularly DNA methylation, plays a crucial role in gene activation and deactivation. Indeed, modification of this pathway has been well described as promoter of cancer development in many settings. Hypermethylation of CpG islands has also been described as a significant epigenetic alteration in prostate cancer (PCa), being associated with gene silencing and tumour progression. Key...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40114836
DOI: 10.21037/tau-24-382

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