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Genomic Analysis of Advanced Phyllodes Tumors Using Next-Generation Sequencing and Their Chemotherapy Response: A Retrospective Study Using the C-CAT Database.

Medicina (Kaunas, Lithuania) - 19 Nov 2024

Suzuki Shuhei, Saito Yosuke

Abstract excerpt

Background and Objectives: Phyllodes tumors are rare breast neoplasms with limited therapeutic options and poorly understood molecular characteristics. This study aimed to analyze genomic alterations and treatment outcomes in advanced phyllodes tumors using Japan's national clinical genomic testing registry (C-CAT database) to identify potential therapeutic targets and predictive markers. Materials and Methods:...

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Identifiers

PMID: 39597083
DOI: 10.3390/medicina60111898
PMCID: PMC11596819

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