Article
Circulating Tumor DNA (ctDNA) is Reliably Detected in Patients with Metastatic Malignant Phyllodes Tumors, a Feasibility Study.
Annals of surgical oncology - 1 Oct 2025
Reason Ellery H, Aiduk Michael D, Nash Amanda L, McDuff Susan G R, Renner Derrick, Kollipara Rahul Krishna, Satta Sandro, Velichko Sharlene, Kalashnikova Ekaterina, Rodriguez Angel A, Liu Minetta C, Strickler John H, Grilley-Olson Juneko E, Rosenberger Laura H
Abstract excerpt
BACKGROUND: Malignant phyllodes tumors (MPT) are biologically aggressive breast neoplasms, with high local and distant recurrence rates and a median survival of 12 months when metastatic. With a disease-free interval often less than 2 years, circulating tumor DNA (ctDNA) may allow for earlier identification of patients with MPT at risk for recurrence. Here, we aim to determine the feasibility of detecting ctDNA...
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