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Article

Molecular pathology of phyllodes tumours of the breast-much more than MED12.

Histopathology - 1 May 2026

Pang Jia-Min B, Gorringe Kylie L, Tan Puay Hoon, Fox Stephen B

Abstract excerpt

Phyllodes tumours of the breast present challenges in their diagnosis, classification and management. Further understanding of the molecular changes underpinning these tumours may lead to more precise classification and potential treatment options. Similar to fibroadenomas, MED12 is the most frequently mutated gene in phyllodes tumour. However, in addition, there is a spectrum of molecular alterations from benign...

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Identifiers

PMID: 41611646
DOI: 10.1111/his.70098
PMCID: PMC13051455

Genes

MED12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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