Article
Role of Ad4-binding protein/steroidogenic factor 1 in regulating NADPH production in adrenocortical Y-1 cells.
Endocrine journal - 31 Mar 2017
Li Bing, Baba Takashi, Miyabayashi Kanako, Sato Tetsuya, Shima Yuichi, Ichinose Tomomi, Miura Daisuke, Ohkawa Yasuyuki, Suyama Mikita, Morohashi Ken-Ichirou
Abstract excerpt
Ad4-binding protein/steroidogenic factor 1 (Ad4BP/SF-1), a member of the nuclear receptor superfamily, is expressed in steroidogenic cells and regulates all steroidogenic gene expression. We recently employed mRNA and chromatin immunoprecipitation sequence (ChIP-seq) to demonstrate that Ad4BP/SF-1 directly regulates the expression of nearly all glycolytic genes. The pentose phosphate pathway (PPP) contributes to...
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