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Article

Coordination of Multiple Cellular Processes by NR5A1/Nr5a1.

Endocrinology and metabolism (Seoul, Korea) - 1 Dec 2020

Morohashi Ken-Ichirou, Inoue Miki, Baba Takashi

Abstract excerpt

The agenesis of the gonads and adrenal gland in revealed by knockout mouse studies strongly suggested a crucial role for Nr5a1 (SF-1 or Ad4BP) in organ development. In relation to these striking phenotypes, NR5A1/Nr5a1 has the potential to reprogram cells to steroidogenic cells, endow pluripotency, and regulate cell proliferation. However, due to limited knowledge regarding NR5A1 target genes, the mechanism by...

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Identifiers

PMID: 33397036
DOI: 10.3803/EnM.2020.402
PMCID: PMC7803590

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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