Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis

13 May 2015

Abstract excerpt

Androgens are essential for sexual development and reproduction. However, androgen regulation in health and disease is poorly understood. We showed that human adrenocortical H295R cells grown under starvation conditions acquire a hyperandrogenic steroid profile with changes in steroid metabolizing enzymes HSD3B2 and CYP17A1 essential for androgen production. Here we studied the regulatory mechanisms underlying...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Lipid metabolism and biosynthesis
Share to Lipid metabolism and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25970467
DOI: 10.1038/srep10132

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesisPMID 25970467Read ↗

Differential activity and expression of human 5β-reductase (AKR1D1) splice variantsSemantic proximity Read ↗

Androgen receptor in human endothelial cellsSemantic proximity Read ↗

Aldo-keto reductase family 1 member C1 regulates the osteogenic differentiation of human ASCs by targeting the progesterone receptorSemantic proximity Read ↗

Expression Profile of Genes Regulating Steroid Biosynthesis and Metabolism in Human Ovarian Granulosa Cells—A Primary Culture ApproachSemantic proximity Read ↗

Regulation of human (adrenal) androgen biosynthesis—New insights from novel throughput technology studiesSemantic proximity Read ↗

Transcriptional Regulation of Steroidogenic Genes: STARD1, CYP11A1 and HSD3BSemantic proximity Read ↗

<i>In Silico</i>Analysis Identifies a Novel Role for Androgens in the Regulation of Human Endometrial ApoptosisSemantic proximity Read ↗

Angiotensin II early regulated genes in H295R human adrenocortical cellsSemantic proximity Read ↗

RNA-binding proteins regulate aldosterone homeostasis in human steroidogenic cellsSemantic proximity Read ↗

Steroidogenic genes expressions are repressed by high levels of leptin and the JAK/STAT signaling pathway in MA-10 Leydig cellsSemantic proximity Read ↗

Steroidogenic factor 1 differentially regulates basal and inducible steroidogenic gene expression and steroid synthesis in human adrenocortical H295R cells.Semantic proximity Read ↗

Retinoic acid and androgen receptors combine to achieve tissue specific control of human prostatic transglutaminase expression: a novel regulatory network with broader significanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.