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Article

Cytochrome b5 modulates multiple reactions in steroidogenesis by diverse mechanisms.

The Journal of steroid biochemistry and molecular biology - 1 Jul 2015

Storbeck Karl-Heinz, Swart Amanda C, Fox Cheryl L, Swart Pieter

Abstract excerpt

Cytochrome b5 (cyt-b5) is a relatively small haemoprotein which plays an important role in the regulation of mammalian steroidogenesis. This unique protein has the ability to modulate the activity of key steroidogenic enzymes via a number of diverse reaction mechanisms. Cyt-b5 can augment the 17,20-lyase activity of CYP17A1 by promoting the interaction of CYP17A1 and POR; enhance the 16-ene-synthase activity of...

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Identifiers

PMID: 25446886
DOI: 10.1016/j.jsbmb.2014.11.024

Genes

POR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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