Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human glutathione S-transferase A (GSTA) family genes are regulated by steroidogenic factor 1 (SF-1) and are involved in steroidogenesis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2013

Matsumura Takehiro, Imamichi Yoshitaka, Mizutani Tetsuya, Ju Yunfeng, Yazawa Takashi, Kawabe Shinya, Kanno Masafumi, Ayabe Tadayuki, Katsumata Noriyuki, Fukami Maki, Inatani Masaru, Akagi Yoshio, Umezawa Akihiro, Ogata Tsutomu, Miyamoto Kaoru

Abstract excerpt

Steroidogenic factor 1 (SF-1) is a master regulator for steroidogenesis. In this study, we identified novel SF-1 target genes using a genome-wide promoter tiling array and a DNA microarray. SF-1 was found to regulate human glutathione S-transferase A (GSTA) family genes (hGSTA1-hGSTA4), a superfamily of detoxification enzymes clustered on chromosome 6p12. All hGSTA genes were up-regulated by transduction of SF-1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Androstenedione
Share to Glutathione Transferase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Isoenzymes

Share to Mesenchymal Stem Cells

Share to Oligonucleotide Array Sequence Analysis

Share to Progesterone

Share to Steroidogenic Factor 1

Share to Steroids

Source

Identifiers

PMID: 23650189
DOI: 10.1096/fj.12-222745

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human glutathione S-transferase A (GSTA) family genes are regulated by steroidogenic factor 1 (SF-1) and are involved in steroidogenesis.PMID 23650189Read ↗

Cloning and sequence analysis of the human gene encoding steroidogenic factor 1Semantic proximity Read ↗

Minireview: steroidogenic factor 1: its roles in differentiation, development, and disease.Semantic proximity Read ↗

Steroidogenic factor 1, an orphan nuclear receptor, regulates the expression of the rat aromatase gene in gonadal tissues.Semantic proximity Read ↗

Beyond steroidogenesis: Novel target genes for SF-1 discovered by genomicsSemantic proximity Read ↗

Steroidogenic Factor 1, a Goldilocks Transcription Factor from Adrenocortical Organogenesis to MalignancySemantic proximity Read ↗

Transcription enhancer factor-5 and a GATA-like protein determine placental-specific expression of the Type I human 3beta-hydroxysteroid dehydrogenase gene, HSD3B1.Semantic proximity Read ↗

Transcriptional Regulation of Steroidogenic Genes: STARD1, CYP11A1 and HSD3BSemantic proximity Read ↗

The Human Sulfotransferase SULT1A1 Gene Is Regulated in a Synergistic Manner by Sp1 and GA Binding ProteinSemantic proximity Read ↗

Regulation of the Human Hydroxysteroid Sulfotransferase (SULT2A1) by RORα and RORγ and Its Potential Relevance to Human Liver DiseasesSemantic proximity Read ↗

Molecular aspects of steroidogenic factor 1 (SF-1).Semantic proximity Read ↗

Transcriptional Regulation of Ovarian Steroidogenic Genes: Recent Findings Obtained from Stem Cell-Derived Steroidogenic CellsSemantic proximity Read ↗

Human alpha class glutathione S-transferases: genetic polymorphism, expression, and susceptibility to disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.