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Article

Consistency of Mycobacterium tuberculosis Complex Spoligotyping between the Membrane-Based Method and In Silico Approach.

Microbiology spectrum - 29 Jun 2022

Genestet Charlotte, Hodille Elisabeth, Bernard Albin, Vallée Maxime, Lina Gérard, Le Meur Adrien, Refrégier Guislaine, Dumitrescua Oana

Abstract excerpt

To tackle the spread of tuberculosis (TB), epidemiological studies are undertaken worldwide to investigate TB transmission chains. Clustered regulatory interspaced short palindromic repeats (CRISPR) locus diversity, also called spoligotyping, is a widely used genotyping assay for the characterization of Mycobacterium tuberculosis complex (MTBC). We compared herein the spoligotyping of MTBC clinical isolates using...

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Identifiers

PMID: 35467406
DOI: 10.1128/spectrum.00223-22
PMCID: PMC9241810

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