Article
Molecular typing of Mycobacterium tuberculosis by using nine novel variable-number tandem repeats across the Beijing family and low-copy-number IS6110 isolates.
Journal of clinical microbiology - 1 Sept 2003
Spurgiesz R Scott, Quitugua Teresa N, Smith Kimothy L, Schupp James, Palmer Eldon G, Cox Rebecca A, Keim Paul
Abstract excerpt
Molecular epidemiological tools for genotyping clinical isolates of Mycobacterium tuberculosis have been developed and used to help track and contain transmission of tuberculosis. We identified 87 short sequence repeat loci within the genome of the M. tuberculosis H37Rv strain. Nine tandem repeats were found to be variable (variable-number tandem repeats [VNTRs]) in a set of 91 isolates. Fifty-seven of the...
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