Diffuse midline glioma H3 K27M-mutant in adults: A report of six cases and literature review.

doi:10.5414/NP301331

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Article

Diffuse midline glioma H3 K27M-mutant in adults: A report of six cases and literature review.

Clinical neuropathology - 1 Jan 2000

Alzoubi Hiba, Maraqa Bayan, Hasasna Nabil, Giangaspero Felice, Antonelli Manila, Gianno Francesca, Arcella Antonella, Al-Hussaini Maysa

Abstract excerpt

AIM: Diffuse midline glioma (DMG) H3 K27M-mutant is a specific entity that, as the name indicates, tends to occur in midline structures including the thalamus, brainstem, and spinal cord. DMG predominates in children, is an aggressive tumor with poor prognosis, and is considered a WHO grade IV tumor regardless of histological features. The exact frequency of these mutations in adults diagnosed with glioma in the...

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PMID: 33191898
DOI: 10.5414/NP301331

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.