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[Diffuse midline glioma with H3K27 alteration in adults: a clinicopathological analysis].

Zhonghua bing li xue za zhi = Chinese journal of pathology - 8 Apr 2023

Yang Q Y, Li M N, Chen T Y, Liu C, Li X, Shi Z M, Pan M H

Abstract excerpt

Objective: To investigate the clinicopathological characteristics, pathological diagnosis and prognosis of diffuse midline glioma (DMG) with H3K27 alteration in adults. Methods: Twenty cases of H3K27-altered adult DMG diagnosed in the First Affiliated Hospital of Nanjing Medical University were enrolled from 2017 to 2022. All cases were evaluated by clinical and imaging presentations, HE, immunohistochemical...

Topics

Humans
Adult
Male
Female
Middle Aged
Aged
Histones
Brain Neoplasms
Proto-Oncogene Proteins B-raf
Glioma
Astrocytoma
Mutation

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PMID: 36973199
DOI: 10.3760/cma.j.cn112151-20220926-00810

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