Article
From somatic mutation to early detection: insights from molecular characterization of pancreatic cancer precursor lesions.
The Journal of pathology - 1 Dec 2018
Fischer Catherine G, Wood Laura D
Abstract excerpt
Pancreatic cancer arises from noninvasive precursor lesions, including pancreatic intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasm (IPMN), and mucinous cystic neoplasm (MCN), which are curable if detected early enough. Recently, these types of precursor lesions have been extensively characterized at the molecular level, defining the timing of critical genetic alterations in tumorigenesis...
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